Nikolova and his colleagues have demonstrated that CD160 acts as a coreceptor in TCR signal transduction in human circulating CD8 + T cells . It plays a protective role during chronic viral …

Sep 2, 2014 · Meanwhile CD160 antibody had no impact on CD4 + T-cell activation in the absence of TCR stimulation, thus suggesting that the CD160 antibody-mediated enhancement …

In this study, we demonstrate that CD160 has a costimulatory role in promoting CD8 + T cell effector functions needed for optimal clearance of oral Listeria monocytogenes infection. …

Sep 25, 2014 · We demonstrate that CD160-associated CD8 T-cell functional impairment is independent of PD-1 expression and that the blockade of CD160 signaling may partially …

Aug 27, 2018 · CD160 is a GPI-anchored protein that is localized in lipid rafts. Therefore, it is possible that CD160 may regulate the activation of TCR proximal signaling. Studies have …

We report that CD160, which has a broad specificity for MHC class Ia and Ib molecules, behaves as a co-receptor upon T cell activation. Anti-CD160 mAb enhance the CD3-induced …

Jan 13, 2008 · The T cell costimulatory protein LIGHT and coinhbitory protein BTLA share a common ligand, HVEM. Now CD160 is also shown to bind HVEM and deliver a potent …

CD160 is an Ig-like glycoprotein expressed by the majority of circulating natural killer cells and γδ T cells. Whether CD160 could regulate CD8 + T-cell functions remains unknown. In this study, …

In the present study, we examined the role of the recently identi®ed glycosylphosphatidylinositol (GPI)-anchored cell surface molecule BY55, assigned as CD160, in TCR signaling.

CD160 is a 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with …