Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a protein that in humans is encoded by the ITGAL gene. …

In cell biology, CD11 is the α (alpha) component of various integrins, especially ones in which the β (beta) component is CD18 (β2) and mediate leukocyte adhesion. [1] . For example, Mac1 …

CD11a is crucial for the optimal expansion of antigen-specific CD8 and CD4 T cells. Although CD11a plays a prominent role in lymphocyte migration to LN , the role of this molecule in CD8 …

CD11a is a panleukocyte marker that is expressed by various types of immune cells, including B- and T-lymphocytes, monocytes, macrophages, neutrophils, basophils, and eosinophils. You …

CD11a is the α chain of the α L β2 integrin (also known as leukocyte function associated antigen 1 [LFA-1]). While CD11a plays a critical role in the homing of lymphocytes across high …

Oct 24, 2013 · CD11a plays a crucial role in AT inflammation by participating in T-cell infiltration and activation. Obesity increases risk for type 2 diabetes mellitus and cardiovascular disease.

Surprisingly, CD8 T cells lacking CD11a mounted a robust secondary response to infection. Taken together, these findings demonstrated that CD11a expression contributes to expansion …

Precise spatiotemporal regulation of leukocyte extravasation is key for generating an efficient immune response to injury or infection. The integrins LFA-1(CD11a/CD18) and Mac …

Apr 9, 2019 · Precise spatiotemporal regulation of leukocyte extravasation is key for generating an efficient immune response to injury or infection. The integrins LFA-1 (CD11a/CD18) and …

Human lymphocyte function-associated antigen-1 (LFA-1, CD11a/CD18, alpha L/beta 2) is a cell surface heterodimer, which, together with Mac-1 (CD11b/CD18, alpha M/beta 2) and p150,95 …