The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells. [1]

The cluster of differentiation (CD) is a protocol used for the identification and investigation of cell surface molecules present on leukocytes. CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell.

Jul 30, 2018 · The popular CD markers are CD138, which is expressed on multiple myeloma cells; CD33 expressed on cells of myeloid lineage; and CD52, which is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes, and macrophages.

Jul 7, 2023 · CD markers, also known as CD antigens, are specific types of molecules found on the surface of cells that help differentiate one cell type from another. In fact, the initials "CD" stands for "cluster of differentiation," the nomenclature of which was first established in 1982.

CD1d-presented lipid antigens activate a special class of T cells, known as natural killer T (NKT) cells, through the interaction with the T-cell receptor present on NKT membranes. T-cell surface glycoprotein CD1e is a protein in humans encoded by the CD1E gene.

Jan 15, 2021 · CD markers refer to a cluster of differentiation (CD), a single or group of molecules on the cell surface that is highly specific to that cell, allowing identification.

C-type lectin; binds ICAM3 and HIV-1 envelope glycoprotein gp120 enables T-cell receptor engagement by stabilization of the DC/T-cell contact zone, promotes efficient infection in trans cells that express CD4 and chemokine receptors; type II transmembrane protein

Feb 20, 2021 · “CD” in immunology stands for Cluster of Differentiation and includes cell surface markers that can be detected by lab technique called flow cytometry. Well, we will just focus on the ones you need to remember at undergraduate level.

CD molecules are surface molecules expressed on cells of the immune system that play key roles in immune cell-cell communication and sensing the microenvironment. These molecules are essential markers for the identification and isolation of leukocytes and lymphocyte subsets.

The CD designation refers to a group of mAbs shown by the statistical method of cluster analysis to recognize a particular cellular differentiation pattern. The CD nomenclature is also used to name the molecule itself. For example, CD4 designates both the group of mAbs recognizing the CD4 cell surface molecule as well as the CD4 molecule itself.