May 14, 2021 · CD Markers - CD13. Granulocytes (most, but low levels in newbornss, Mod Pathol 1993;6:414), interdigitating dendritic cells, large granular lymphocytes (some), macrophages, mast cells, monocytes, myelomonocytes and osteoclasts

Jun 13, 2024 · Involved in cell proliferation, migration, adhesion and angiogenesis with loss of CD138 expression leading to enhanced motility and invasion of neoplastic cells (Oncotarget 2015;6:28693)

Jan 17, 2023 · Encoded by MME gene ; 85-110 kDa cell membrane metalloendopeptidase at 3q25.1-q25.2 that inactivates bioactive peptides, including atrial natriuretic factor, bombesin, β amyloid, endothelin 1, enkephalins, gastrin and substance P and through the cytoplasmic domain, directly interacts with ezrin / radixin / moesin proteins, Lyn kinase and the phosphatase and tensin homolog (PTEN) protein (J ...

CD30 specific chimeric antigen receptor T (CAR T) cells (Blood Cancer J 2017;7:e603, J Clin Oncol 2020;38:3794, Sci Rep 2022;12:10488, Front Immunol 2022;13:858021) 3 generations of anti-CD30 CAR T cells Phase I / II studies in relapsed / refractory CHL Association with anti-PD1 regimen can improve the efficacy of CD30 CAR T therapy

Epithelioid cell histiocytoma (diffuse) (Diagn Pathol 2018;13:28) Perianal atypical fibrous histiocytoma (focal) (Am J Dermatopathol 2014;36:171) Multinucleate cell angiohistiocytoma (interstitial histiocytes) (J Cutan Pathol 2013;40:1048) Sinonasal hemangiopericytoma (Am J Otolaryngol 2017;38:87, Int J Clin Oncol 2012;17:169)

Mar 19, 2024 · Most T cells, activated B cells, B cells in terminal ileum (Appl Immunohistochem Mol Morphol 2005;13:138), plasma cells (Scand J Immunol 1991;33:211) Basophils, erythrocytes, granulocytes, hematogones ( Br J Haematol 2005;128:820 ), macrophages (some), megakaryocytes, monocytes, NK cells, platelets (weak)

Apr 9, 2025 · CD Markers - CD130-139. Also known as Prominin 1, AC133 Transmembrane glycoprotein expressed on the hematopoietic stem cells, endothelial progenitors and dermal derived stem cells capable of differentiating into neural cells

May 5, 2022 · Mixture of 2 different clones of anticytokeratin monoclonal antibodies (AE1 and AE3), which functions as a broad spectrum cytokeratin marker for cytokeratins 1 - 8, 10, 14 - 16 and 19

4 days ago · Mutations in CD45 have been implicated in cases of autosomal recessive T cell negative, B cell positive, NK cell positive severe combined immunodeficiency (Immunol Lett 2018;196:22, OMIM: Severe Combined Immunodeficiency, Autosomal Recessive, T Cell Negative, B Cell Positive, Nk Cell Positive [Accessed 13 January 2022])

Mar 21, 2023 · As per the upcoming 2022 5th edition of WHO classification, acute myelomonocytic leukemia (AMML) is a distinct entity within acute myeloid leukemia, defined by differentiation category