C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. [5] . Two ligands have been identified for this receptor: the chemokines (C-C motif) ligand 19 …

Recent evidence suggests that by guiding cells to and within lymphoid organs, CC-chemokine receptor 7 (CCR7) essentially contributes to both immunity and tolerance.

CC‑chemokine receptor 7 (CCR7) is well known to direct adaptive immune cell migration to secondary lymphoid tissues (Fig. 3) [44]. CCR7 is expressed by various lymphocytes, …

Mar 30, 2025 · CCR7 (C-C Motif Chemokine Receptor 7) is a Protein Coding gene. Diseases associated with CCR7 include Chronic Graft Versus Host Disease and Tetanus. Among its …

Growing evidence suggests that cell trafficking orchestrated by the C-C chemokine receptor 7 (CCR7) plays a critical role in the pathophysiology of several leukemias and lymphomas.

Chemokine receptors promote chemotaxis of cells and tissue organization. Since under homeostatic conditions, CCR7 promotes migration of immune cells to lymph nodes, questions …

May 1, 2023 · Recent studies have revealed that the C–C chemokine receptor 7 (CCR7) is expressed in both CNS resident cells and peripheral immune cells, and plays an important role …

Aug 17, 2017 · Our study indicates that CCR7 homodimerization critically regulates CCR7 ligand-dependent cell migration and intracellular signaling in multiple cell types. Recruitment of …

Oct 22, 2019 · Here, we uncover a function for an intracellular pool of the chemokine receptor CCR7 present in human dendritic cells and cellular model systems. We find that CCR7 …

Jan 24, 2024 · We report that CCR7 + DCs are the dominant DC population that migrate to the dLN, but a subset remains tumour-resident despite CCR7 expression. These tumour-retained …