Dec 4, 2019 · Here, we demonstrated that macrophage infiltration induced by lipopolysaccharide (LPS) or a high-cholesterol diet (HCD) significantly promoted CRC growth. Similarly, LPS and …

Overexpression of CCL5 was found in LPS-treated cells. CCL5 silence protected WI-38 cells from LPS-induced inflammatory damage, with increasing cell viability, inhibiting cell apoptosis, and …

Our results suggest that the novel CCL5-p65/STAT3-CSN5-PD-L1 signaling axis is significantly activated by LPS or HCD-driven macrophage infiltration in an animal model of CRC, which …

CCL5 silence protected WI-38 cells from LPS-induced inflammatory damage, with increasing cell viability, inhibiting cell apoptosis, and reducing the production of pro-inflammatory cytokines. …

Feb 15, 2021 · CCR5 inhibition partially restored the alveolar development impaired by LPS in vitro. CCR5 and its ligands enhanced macrophage migration to lungs, which overproduced IL …

Aug 15, 2017 · Moreover, CCL5 neutralization reduced the LPS-induced TNF-α and IL-10 secretion (45.0 and 52.1% reduction from isotype) from rMs stimulated ex vivo with LPS (Fig. …

May 21, 2012 · Among the nine LPS-responsive chemokines examined, mRNA induction of ccl5, cxcl10, and cxcl13 is mediated through the MyD88-independent pathway. Notably, Cot/Tpl2 …

To further investigate the mechanism responsible for mucosal protection mediated by CCL5-CCR5 signaling, we evaluated the effects of CCL5 on B cells. CCL5 enhanced proliferation …

Jul 1, 2019 · SNHG16 regulated LPS-induced inflammation injury in WI-38 cells through competitively binding miR-146a-5p with CCL5 further mediating JNK and NF-κB pathways, …

Jan 23, 2012 · We found in this study that chemokine CCL5, IP-10 and MCP-1 have different kinetics after balloon injury. In SMCs IFN-γ enhances LPS-induced CCL5 transcription and …