It provides the United States Air Force (USAF) with a heavy intercontinental-range strategic airlift capability, one that can carry outsized and oversized loads, including all air-certifiable cargo. …

C5a is a protein fragment released from cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments.

Dec 18, 2017 · With its new engines and other system upgrades, the RERP modified C-5A/B/Cs became C-5M Super Galaxies.

Herein, we review human and animal data describing the cellular and molecular mechanisms of C5a in the development of inflammatory disorders, sepsis, acute lung injury, ischemia …

Its primary mission is to transport cargo and personnel for the Department of Defense. The C-5M is a modernized version of the legacy C-5 designed and manufactured by Lockheed Martin. …

Aug 7, 2013 · As the Air Force’s largest strategic airlifter, the C-5 Galaxy can carry more cargo farther distances than any other aircraft. With a payload of six Mine Resistant Ambush …

The C5a receptor also known as complement component 5a receptor 1 (C5AR1) or CD88 (Cluster of Differentiation 88) is a G protein-coupled receptor for C5a. It functions as a …

This review provides a comprehensive overview of human C5a in the context of its structure and signaling under several pathophysiological conditions, including the current and future …

The C5 complement component, a part of the innate immune system, plays an important role attacking various infectious agents. C5a and C5b, proteolytic fragments of C5, are highly …

The hC5aR2, unlike hC5aR1, binds C5a and C5a des Arg using distinct mechanisms, with its N-terminus containing Tyr and acidic residues critical for binding of C5a des Arg but not of C5a. …