000664 C57BL/6J C57BL/6J is the most widely used inbred strain and the first to have its genome sequenced. Although this strain is refractory to many tumors, it is a permissive background for maximal expression of most mutations. C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss.

Study-ready aged C57BL/6J males and females are available off-the-shelf between 25 - 78 weeks of age. Aged C57BL/6J mice have research applications that include immunology, cancer, longevity interventions, and biomarker studies. C57BL/6J is the most widely used inbred mouse strain and the first to have its genome sequenced. C57BL/6J mice are resistant to audiogenic seizures, have a relatively ...

The same cross gave rise to strains C57L and C57BR. Female 58 mated with the same male gave rise to strain C58. C57BL is probably the most widely used of all inbred strains, (substrain C57BL/6 alone accounts for over 14% of occasions on which an inbred strain is used) though in many ways it seems to be atypical of inbred strains of laboratory mice.

Because of its high alcohol preference, C57BL/6J has been used by some researchers to examine the mode of inheritance and the effects of alcohol on mice of different ages. Blacks are also one of the oldest inbred strains. While at Cold Spring Harbor in 1921, Little started a new "family of mice" descended from mice received from Miss Abby ...

Apr 4, 2013 · C57BL/6J and C57BL/6N vary in their fear responses (Radulovic et al. 1998; Stiedl et al. 1999) and how anesthetics affect their cardiac functions (Roth et al. 2002). C57BL/6N mice and embryonic stem cells derived from them harbor the Rd8 mutation of the Crb1 gene, which causes developmental defects in photoreceptor segments ( Mehalow et al ...

Jun 22, 2016 · The popularity of C57BL/6 inbred mice led to the establishment of many colonies at different vendors and academic institutions around the world. C57BL/6 substrains. You may not know this: every time a new C57BL/6 colony is maintained separately from an existing colony for 20 or more generations, it becomes a new C57BL/6 substrain.

Mar 18, 2025 · C57BL/6J Strain Detail Summary Strain Name. C57BL/6J Attributes. inbred strain MGI ID. MGI:3028467. Synonyms. B6, B6J, Black 6, C57 Black Collection. DO/CC Founder Phenomic Data. Mouse Phenome Database (MPD) Mouse Genome Browsers. Multiple Genome Viewer (MGV) Other IDs. MGI:2159736, MGI:3720861, JAX:000664, MPD:7 ...

005304 C57BL/6NJ This is an NIH subline of C57BL/6. It was separated from C57BL/6J in 1951. Five SNP differences have been identified that distinguish C57BL/6J from C57BL/6ByJ and C57BL/6NJ. This strain does not have the deletion in the Nnt gene that has been found in the C57BL/6J strain (Stock No. /000664">000664</a>).

C57BL/6NTac exact match to ID References Earliest. J:62168 Means GD, et al., A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation. Genomics. 2000 May 1;65(3):213-23. All. 107. Contributing Projects: ...

Mar 25, 2025 · C57BL/6N Attributes. inbred strain MGI ID. MGI:2159965. Phenomic Data. Mouse Phenome Database (MPD) Other IDs. MPD:138 Associated Mutations, Markers, and QTL 2 associated mutations Show All. Mutation Carried Marker; Crb1 rd8: Crb1: Cyfip2 M1N: Cyfip2: 23 associated QTL Show All. Allele Marker; Bbaa10 C57BL/6N: Bbaa10 ...