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C57BL/6, often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common inbred strain of laboratory mouse. It is the most widely used "genetic background" for genetically modified mice for use as models of human disease.

C57 MOUSE mouse. svg. 1948. Long Li @Long92335990. 10.5281/zenodo.5496316. Scidraw, coded with love by Federico and Alex. @scidrawio. Thank you to everyone who uploaded drawings to Scidraw. Scidraw is supported by the Sainsbury Wellcome Centre. All ...

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C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss. They are also susceptible to diet-induced obesity, type 2 diabetes, and atherosclerosis.