Jul 6, 2021 · WHAT DOES IT MEAN IF YOUR COMPLEMENT C4A RESULT IS TOO HIGH? If your results show higher than normal amounts or increased activity of complement proteins, it may mean you have one of the following conditions: – Certain types of cancer, such as leukemia or non-Hodgkin lymphoma. – Levels will be increased in …

Feb 25, 2024 · What Does High Complement C4 Mean? There are several reasons why you might have high complement C4 levels over 45 milligrams per deciliter. If you have had a recent injury or infection,...

Mar 2, 2020 · Information is sparse on C4A, but I’ve tried to gather what there is. C4A is often elevated in chronic inflammation. What is C4A? C4A is part of a “complement” group. The term complement means it is able to kill bacteria and contributes to immune defenses.

What does it mean if your Complement C4a result is too high? Elevation of C4a levels is not predictive of any specific disease. Complement C4a levels can become increased in any condition associated with inflammation.

Dec 15, 2022 · Complement C4 is a protein that is important for your immune function. It helps clear infections and protects against autoimmunity. Low levels may point to autoimmune disease, including lupus. High levels are rare, poorly understood, and may signal inflammation. Read on to find out more about the C4 test. What is Complement C4? Overview

Oct 24, 2024 · What do high levels of C4 mean? High C4 protein levels may mean you’re recovering from an infection or illness. If you’re getting treatment for an autoimmune disease, high C4 typically means treatment is working. High C4 levels may also be a sign of the following health conditions: Ulcerative colitis. Sarcoidosis (inflammatory disease).

Jul 3, 2019 · The complement component 4 (C4) assay is a test used to detect the quantity of C4 complements present in human serum or plasma. Know what are the conditions caused by high complement c4 levels and even get the interpretation of results

C4A is named after its acidity and migrates faster in agarose gel electrophoresis as compared to C4B that is basic and migrates slower (47–51). In addition, C4A and C4B are highly polymorphic with more than 40 different alleles, gene duplications, and “null alleles” (52–55).

What does it mean if your C4a Level by RIA result is too high? Elevated levels of C4a, a fragment of the complement protein C4, can be a sign of increased immune system activity, often occurring in response to inflammation, infection, or autoimmune disorders.

Complement cascade activation results in the formation of complement split products C 3 a, C 4 a, and C 5 a. 4 These proteins, referred to as anaphylatoxins, facilitate the phagocytosis of immune complexes, viral particles, toxic cell debris and apoptotic corpses.