A spontaneous mutation in <em>Tlr4</em> occurred in C3H/HeJ at the lipopolysaccharide response locus (mutation in toll-like receptor 4 gene, <em>Tlr4^Lps-d</em>) …

C3H mice were first developed in 1920 in the United States by Haldane. In 1930, Snell extensively inbred this strain. They are known for their susceptibility to a wide range of pathogens and …

C3H/HeOuJ mice and all other C3H substrains at The Jackson Laboratory are homozygous for the retinal degeneration 1 mutation (<i>Pde6b^rd1</i>), causing blindness by …

Genet: +, rd. Developed by Strong 1920 from a cross of Bagg albino with DBA male (see CBA) with selection for a high incidence of mammary tumours. Now among the most widely used of …

Jan 12, 2025 · C3H/HeN mice are distinguished by their unique genetic profile, meticulously characterized over decades of research. These mice belong to the C3H strain, a lineage …

Mar 18, 2025 · View mouse strain C3H/HeJ : mutations, QTL, phenotypes, diseases, and references.

General purpose strain used in a wide variety of research areas including cancer and sensorineural research. Origin: The C3H parent strain was developed by LC Strong in 1920 …

C3H is a high body weight strain reported to exhibit some features of “metabolic syndrome”, with a tendency for substantial food intake under ad lib. conditions and notably high cholesterol and …

Charles River breeds laboratory mice, such as the C3H, for use in basic research and nonclinical drug discovery and development.

Aug 6, 2024 · The C3H/HeJ mouse AA model, induced by either full-thickness skin grafts or cell transfer, has yielded a highly reproducible tool to work out the pathogenesis of this …