This review summarizes the current advances on the BES1/BZR1 family transcription factors, the mechanisms regulating their activities, DNA binding motifs, target genes, and their biological functions in regulating growth and development. We highlight a number of findings on the roles of the BES1/BZR1 family within the last a few years. 2.

Mar 1, 2025 · Brassinosteroids (BR) are ubiquitous polyhydroxylated steroid hormones in plants that play a pivotal role in orchestrating plant growth, development, and stress mitigation. The transcription factor BRI1 EMS SUPPRESSOR 1/BRASSINAZOLE RESISTANT 1 (BES1/BZR1) is central to BR signal transduction.

Nov 8, 2021 · We evaluated the transcriptional alterations in Mp bes1 mutants through RNA sequencing (RNA-seq) of 2-week-old WT and mutant regenerating thalli. We found 3,246 deregulated genes in the mutant (|fold-change| > 1.5; false discovery rate [FDR] < 0.05).

Jun 1, 2018 · BZR1 and BES1 are key transcription factors of brassinosteroid (BR) signaling and represent the integration node of numerous signaling cascades. Their direct target genes have been identified, and BZR1/BES1-DNA interactions have been experimentally verified.

Jun 17, 2021 · To investigate the role of BZR1 in BR-mediated AMT1 induction, BZR1 RNAi (#1), the knockdown transgenic line, and bzr1-D dominant mutant line were constructed (Bai et al., 2007; Ren et al., 2020).

Nov 5, 2023 · Brassinazole Resistant 1 (BZR1) and bri1 EMS Suppressor 1 (BES1) are key transcription factors that mediate brassinosteroid (BR)-responsive gene expression in Arabidopsis. The BZR1/BES1 family is composed of BZR1, BES1, and four BES1/BZR1 homologs (BEH1-BEH4).

Oct 7, 2019 · This study shows that BZR1 family transcription factors (BZRs) are indispensable for both BR signaling and anther development. BZRs regulate anther development by affecting the expression of SPL, but via a mechanism that is independent of known BR receptors.

Dec 4, 2023 · This study finds that two subunits of V-ATPase, VHA-a2 and VHA-a3, interact with BZR1 in the tonoplast through a conserved domain, reducing total and nuclear-localized BZR1 and the nuclear BZR1/phosphorylated BZR1 ratio.

2 days ago · The ZmBES1/BZR1-4 acts as a BES1/BZR1 TF, negatively regulates drought tolerance but positively controls seed size and influences starch and fatty acid metabolism. The ZmBES1/BZR1-4 recruits ZmTLP5 t...

Using RNAi suppression of OsBZR1 expression, we demonstrated an essential role of OsBZR1 in BR responses in rice. We further identified the rice 14-3-3 proteins as OsBZR1-interacting proteins.