Bromodeoxyuridine (5-bromo-2'-deoxyuridine, BrdU, BUdR, BrdUrd, broxuridine) is a synthetic nucleoside analogue with a chemical structure similar to thymidine. BrdU is commonly used to study cell proliferation in living tissues [1] and has been studied as a radiosensitizer [2] and diagnostic tool in people with cancer.

Apr 22, 2019 · Using this method, we detect 5-bromodeoxyuridine (BrdU) incorporated by Saccharomyces cerevisiae to reveal, at a genomic scale and on single molecules, the DNA sequences replicated during a...

BrdU (Bromodeoxyuridine) is a commonly used tool for cell proliferation and cell cycle studies. We look at its structure and use and provide useful resources and product information.

As markers of DNA synthesis, [3 H]thymidine ( [3 H]dT) and the later developed analog bromodeoxyuridine (BrdU) have revolutionized our ability to identify dividing cells and follow …

The synthetic halogenated pyrimidine analog, 5-bromo-2′-deoxyuridine (BrdU), is a marker of DNA synthesis. This exogenous nucleoside has generated important insights into the cellular mechanisms of the central nervous system development in a variety ...

5-Bromo-2'-deoxyuridine (BrdU) is effectively incorporated into the newly synthesised DNA by cellular DNA polymerases. Therefore, it is often used for the visualisation of cellular replicational activity. For BrdU detection, special antibodies raised against BrdU are necessary.

Nov 2, 2006 · Neurogenesis within the adult central nervous system is demonstrated using an exogenous cell tracer, 5'-bromo-2'-deoxyuridine (BrdU), in combination with endogenous neuronal markers.

Bromodeoxyuridine (brdu) | C9H11BrN2O5 | CID 2729613 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Bromodeoxyuridine (BrdU) is the thymidine analog most frequently used. It is incorporated into DNA during the S-phase of the cell cycle, during which DNA is single stranded and BrdU can bind to the thymidine base pair, adenosine. As this only occurs during a fraction of the cell cycle, BrdU only labels a fraction of mitotic cells.

BrdU is a synthetic nucleoside analog, like the nucleoside thymidine, except the methyl group is replaced with a bromine atom. BrdU can be incorporated into DNA whenever thymidine normally would be, including during DNA replication and repair.