Dec 13, 2023 · We systematically analysed the neuronal and non-neuronal cell types across the brain and identified a high degree of correspondence between transcriptomic identity and spatial specificity for...

Mar 24, 2025 · Our study extends the understanding of the spatial organization of diverse cell types in the mouse brain, revealing their distinct laminar and regional distribution patterns that align with brain function and disease relevance.

Jun 11, 2018 · Elucidating brain cell type specific gene expression patterns is critical towards a better understanding of how cell-cell communications may influence brain functions and dysfunctions.

The Allen Brain Cell (ABC) Atlas provides a platform for visualizing multimodal single cell data across the mammalian brain and aims to empower researchers to explore and analyze multiple whole-brain datasets simultaneously.

Nov 21, 2024 · The functional properties of the human brain arise, in part, from the vast assortment of cell types that pattern the cerebral cortex.

May 17, 2023 · The current sc BrainMap database contains 4881 cell types with 26 044 genetic markers identified from 6 577 222 single cells, which link to 14 species, 124 brain regions and 20 different disease states. sc BrainMap enables users to perform customized, cross-linked, biologically relevant queries for different cell types of interest.

Aug 9, 2024 · Brain organoids bear an uncanny resemblance to a miniaturized brain. They can be prepared from anyone by taking a few skin or blood cells, converting them to stem cells, and differentiating them to neurons with simple methods that …

Oct 31, 2024 · The method—known as START, or “single transcriptome assisted rabies tracing”—organizes cells into groups based on their gene expression and traces their connections. If a group shows distinct connectivity patterns, it likely represents a distinct subtype, the study suggests.

4 days ago · The researchers found that cells in the cerebral cortex that were activated when the mice noticed the whisker-flick projected down to deeper brain regions, including the thalamus.

Sep 25, 2024 · The study, published in the journal Nature, directly recorded the activity of individual neurons in humans and found specific types of brain cells fired in a way that mostly mirrored the order and structure of a person’s experience.