This environmentally sustainable strategy generated the desired products in excellent yields. The reaction involved the carbene formation of aryl diazoesters from a blue LED and a subsequent generation of pyridine ylides.

Jun 28, 2022 · The blue LED-promoted P–S, P–Se, and P–Te bond constructions occurred under metal-free, ligand-free, oxidant-free, and photocatalyst-free conditions with minimum chemical waste generation and high atom economy providing the resulting phosphorochalcogenoates, phosphorochalcogenothioates, and phosphinothioates in good to excellent yields.

Jan 29, 2020 · We interview Jefferson researcher on how he is synthesizing molecules that could help treat diseases like cancer, with the help of a little blue light.

Dec 1, 2024 · Herein, we demonstrated the optimization of a blue LED (450 nm) induced C-C bond formation between various aryl and heteroaryl aldehydes with 1,4-quinones at room temperature in ethyl acetate using Design of Experiments (DoE).

Jan 8, 2021 · Mild blue light-mediated N–H insertion of indole and its derivatives into aryldiazoesters has been reported in a batch and flow strategy to afford the corresponding N-alkylated product in moderate-to-excellent yield.

Aug 4, 2022 · The synthesis of (E)-diphenyl (aryldiazenyl)phosphine oxides and dialkyl (E)- (aryldiazenyl)phosphonates via visible light-mediated N–P bond formation between diazo species and phosphine oxides and phosphite derivatives, respectively, is described.

Aug 19, 2023 · A three-component reaction of olefins, indoles, and diaryl diselenides catalyzed by copper chloride under irradiation of blue LED light is disclosed. Various diaryl diselenides including diheteroaryl diselenides are suitable for this bifunctionalization of olefins.

Jan 26, 2022 · The blue LED and copper-based molecular catalyst combo generates a cross-coupling reaction, in which two molecules are joined via a carbon-carbon bond. It’s a widely used type of reaction essential for creating the majority of chemical products today.

Oct 22, 2022 · This preliminary reaction revealed that aryl acetates could be a suitable substrate for the synthesis of α-ketoamides in blue LED without the isolation of the diazo intermediate, provided the reaction happens in presence of an appropriate oxidant.

Sep 4, 2023 · For the first time, we analyzed the effect of blue LED irradiation on this reaction and found that when blue LEDs are used as the light source, a Cu 2 O/CuO ratio of 0.15 results in rate constants 7 to 3 times higher than those of catalysts with …