Several investigations have been performed (i) to obtain bioactive glasses in different forms, such as bulk materials, powders, composites, and porous scaffolds and (ii) to investigate their possible applications in the biomedical field.

BIOGLASS AS ANTIBACTERIAL AGENT. The reactions of bioglass in aqueous environment, leading to osseointegration prompted scientists to check its antibacterial activity.

Bioglass ® is a silicate glass, thus characterized by the presence of silica (SiO 2) as a network forming oxide where the basic unit is the SiO 4 tetrahedron. Each unit shears up to 4 oxygen atoms allowing the creation of the 3D network and connects to …

Bioglass 45S5 is the first formulation of an artificial material that was found to chemically bond with bone, and its discovery led to a series of other bioactive glasses. One of its main medical advantages is its biocompatibility, seen in its ability to avoid an …

Aug 15, 2023 · Bioglass is a bioactive glass that has been shown to promote bone regeneration and bonding when implanted in vivo. Combining bioglass with polymers can improve the mechanical properties of the resulting composite and also enable the composite to be fabricated into various shapes and sizes.

Bioglass® involves a rapid chemical reaction at its surface after implantation in living tissue [13]. First, the elution of Ca 2 + and Na + ions and the hydrolysis of the silica glass network proceed, and a hydrated silica layer enriched with silanol (Si-OH) groups is formed on the glass surface.

Jan 15, 2011 · In this work, a novel mathematical model is proposed to numerically analyze the dissolution and bioactivity of bioactive glasses in relevant conditions for their in vitro and in vivo applications.

Mar 28, 2025 · Additionally, the addition of 2 mol% Sm 2 O 3 to a bioglass–hydroxyapatite composite decreases the degree of adhesion of Staphylococcus aureus and Staphylococcus epidermidis, ... After the complete addition of calcium nitrate, the reaction mass was stirred for 15 min, after which 16.8 g (0.198 mol) of sodium nitrate was added in portions of 2 ...

During this activation period, the bioactive glass goes through a series of chemical reactions, creating the ideal conditions for the bone to rebuild through osteoconduction. Na, Si, Ca, and P ions are released.

Bioactive glasses (BGs) are especially useful materials in soft and bone tissue engineering and even in dentistry. They can be the solution to many medical problems, and they have a huge role in the healing processes of bone fractures. Interestingly, they can also promote skin regeneration and wound healing.