Bioburden is normally defined as the number of bacteria living on a surface that has not been sterilized. [1] The term is most often used in the context of bioburden testing, also known as microbial limit testing, which is performed on pharmaceutical products and medical products for quality control purposes.

Nov 16, 2022 · Bioburden testing is a recommended method for determining the total quantity and types of viable microorganisms in unsterilized material or products before performing sterilization.

Nov 9, 2021 · What is bioburden and how is it measured? Simply put, bioburden is the number of contaminated microorganisms found in a given amount of material before a sterilisation procedure is carried out. Bioburden levels are measured in terms of colony-forming units (CFUs).

Aug 6, 2024 · Bioburden aims to evaluate the quantity and species of living microorganisms on a medical device before sterilization, whereas sterility testing aims to ensure that no more living microorganisms remain on a medical after sterilization.

Bioburden testing or Microbial testing is a quality control process that detects and quantifies microbial contamination of a product at different stages of production i.e., from initial manufacturing to final distribution.

Bioburden is a term used to describe the microbial numbers on a surface (or complete item) or inside a device or from a portion of liquid.

Dec 10, 2024 · Bioburden testing is a critical component in the pharmaceutical, medical device, and biotechnology industries. This process assesses the microbial load on a product or surface, ensuring safety and compliance with regulatory standards.

May 22, 2024 · Bioburden testing measures microbial life on medical devices before sterilization, crucial for patient safety and compliance with international standards. Learn why it is vital in the health care setting.

Feb 21, 2025 · Bioburden testing is the process of determining the total number of viable microorganisms (Total Viable Count) present in or on a medical device. This testing is crucial for medical device manufacturers in ensuring a high level of …

Learn about bioburden and discover effective strategies for bioburden control and reduction to mitigate the risk of microbial contamination.