The BCL2 associated agonist of cell death [5] (BAD) protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis. BAD is a member of the BH3-only …

Mar 28, 2025 · BAD (BCL2 Associated Agonist Of Cell Death) is a Protein Coding gene. Diseases associated with BAD include B-Cell Lymphoma and Transient Cerebral Ischemia. Among its …

Feb 21, 2011 · The Bcl-2-associated death promoter (BAD) protein, like many other BH3-only proteins, is known to promote apoptosis through the intrinsic mitochondrial pathway. Unlike the …

Mar 15, 2025 · This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. …

Bcl-2 蛋白家族通过控制线粒体通透性来调节细胞凋亡。抗凋亡蛋白 Bcl-2 和 Bcl-xL 驻留在线粒体外膜中，抑制 cytochrome c 释放。促凋亡的 Bcl-2 蛋白 Bad、Bid、Bax 和 Bim 可驻留在细胞 …

5 days ago · Bad is a proapoptotic member of the Bcl-2 family that promotes cell death by displacing Bax from binding to Bcl-2 and Bcl-xL (1,2). Survival factors, such as IL-3, inhibit the …

Mar 1, 2024 · BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell …

BAD is a pro-apoptotic member of the Bcl-2 family that is tightly regulated by survival factors. Several major signalling pathways influence cell death through their direct effects on the...

6 days ago · The family is composed of proapoptotic (prodeath) proteins such as BAK, BAX, BAD, BID, NOXA, and others as well as antiapoptotic (prosurvival) proteins such as BCL-2, BCL-XL, …

Aug 6, 2001 · The pro-apoptotic molecule BAD binds BCL-xL or BCL2 and inactivates their survival function. In addition to their anti-apoptotic function, BCL2 and BCL-xL also delay cell …