BT-474 is a cell line exhibiting epithelial morphology that was isolated from a solid, invasive ductal carcinoma of the breast obtained from a 60-year-old, White, female breast cancer patient. Use these cells in your cancer research.

BT-474 Clone 5 is an epithelial-like cell line clone that was originally isolated from the mammary gland of a 60-year-old, White female patient with ductal carcinoma. BT-474 (ATCC HTB-20) cells were grown in 10ug/mL Herceptin for several weeks until the resulting cells (clones) were defined as resistant to Herceptin treatment. These resistant ...

BT-474-Luc2 CAR-T Target Luciferase Reporter Cells can be used as a target cancer cell for in vitro killing assay by HER2 CAR-T cells (tested at ATCC). BT-474 naturally expresses high levels of the gene HER2 (verified at ATCC).

BT-474 is a human breast cancer cell line that was established from a primary tumor in a patient with breast cancer. It is commonly used as a model for studying the biology of breast cancer, which is the second most common cancer in women worldwide and is associated with a significant mortality rate.

May 1, 2020 · Optimization of our BT-474 breast cancer model in NSG mice has been a significant advancement of our validated breast tumor models, and we are continuing to evaluate other HER2 targeted therapies, such as Herceptin, in the BT-474 model.

A human breast tumor cell line (BT-474) that supports mouse mammary tumor virus replication. In Vitro 15:723-729(1979) DOI=10.1007/978-1-4757-0019-0_7 Lasfargues E.Y., Coutinho W.G. Human breast tumor cells in culture; new concepts in mammary carcinogenesis.

Spotlight on BT-474 Human ductal breast carcinoma Learn more about this cell line in our scientific spotlights: The BT-474 cell line has a long history, but many of us thought it had run its natural course and was quickly becoming obsolete.

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates.

A human breast tumor cell line (BT-474) that supports mouse mammary tumor virus replication. In Vitro 15: 723-729, 1979. PubMed: 94035 Littlewood-Evans AJ, et al.

BT-474 is a human breast cancer cell line, derived from the ductal carcinoma of a 60-year-old female. This cell line is estrogen and progesterone receptor positive, making it a valuable model for studying hormone-responsive breast cancers. BT-474 cells are also characterized by the overexpression of HER2/neu (human