Jul 2, 2024 · This review article illustrates the function of branched-chain amino acids (BCAAs - essential nutrients we get from food) and how they’re processed in our bodies, in relation to …

Aug 5, 2022 · Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes …

Feb 5, 2019 · Here, we employ in vivo isotopic tracing to systemically quantify BCAA oxidation in healthy and insulin-resistant mice. We find that most tissues rapidly oxidize BCAAs into the …

Nov 23, 2023 · Branched Chain Amino Acids (BCAAs) are a group of three essential amino acids that play a crucial role in protein synthesis and energy production within the body. The three …

Branched chain amino acids (BCAAs), leucine, isoleucine and valine, are essential amino acids widely studied for their crucial role in the regulation of protein synthesis mainly through the …

May 3, 2018 · Increased BCAA concentrations during brief starvation and type 1 diabetes are explained by amination of BCKAs in visceral tissues and decreased uptake of BCAA by …

Jan 23, 2017 · BCAA are catabolized to acetyl-CoA and/or succinate-CoA and subsequently enter the TCA cycle. The main steps of the catabolic reactions (transamination by BCAT and …

Jun 1, 2005 · Transamination provides a mechanism for dispersing BCAA nitrogen according to the tissue's requirements for glutamate and other dispensable amino acids.

In this review, we summarize the latest studies on the metabolic regulation of BCAA homeostasis by the three major metabolic tissues—adipose tissue, skeletal muscle, and liver—and how …

Although it is widely used as a dietary supplement to delay the aging process in humans, recent evidence suggests that branched-chain amino acids (BCAAs) might be a major cause of the...