Discover the world of advanced bioengineering with ATUM – your life science partner! Integrated solutions accelerate timelines from discovery to manufacturing, preclinical research to IND applications.

ATUM is based in the US, with a global customer base encompassing academia, government and the pharmaceutical, chemical, agricultural and biotechnology industries. ATUM is by far the most published synthetic biology vendor, providing expert support to and collaboration with scientists.

ATUM's efficient workflow integrates in-house-media, assay, analytical and process development expertise. This accelerates project timelines and positions your protein for fast scale-up and manufacturing.

ATUM's transient & stable mammalian vectors support high levels of expression in HEK and CHO cells, and allow efficient genomic integration of expression constructs.

ATUM is building on DNA2.0’s reputation for rapid, reliable, and accurate DNA synthesis. Using our proprietary AI/ML based GeneGPS ® and VectorGPS ® platforms we design constructs optimized to express in your system, whether that’s a single gene in E. coli, a metabolic pathway in yeast or a complex bispecific antibody in mammalian cells.

ATUM currently uses two mammalian host cell lines with lineage traceability and documented provenance. All CHO cell lines are adapted to commercially-available chemically-defined serum-free formulations.

Use the ATUM Expression Test to determine the best vector for your construct. ATUM will clone and test your construct in a full bacterial vector panel to quickly determine expression levels in E. coli.

Mammalian Expression Vectors ATUM offers a range of bacterial expression vectors. Combinations of different promoters, selectable markers, and copy numbers

CRISPR gRNA Design tool lets you design gRNA(s) to efficiently engineer your target and minimize off-target effects using ATUM Scoring Algorithms.

ATUM’s CRISPR vectors comprise a gene encoding the Cas9 nuclease, and a cassette for expressing the guide RNA which targets the nuclease. Cas9 nucleases are directed by a 20nt guide sequence to cleave almost any genomic locus.