ATOX1 is an abbreviation of the full name Antioxidant Protein 1. The nomenclature stems from initial characterization that showed that ATOX1 protected cells from reactive oxygen species.

Mar 28, 2025 · Complete information for ATOX1 gene (Protein Coding), Antioxidant 1 Copper Chaperone, including: function, proteins, disorders, pathways, orthologs, and expression.

Apr 4, 2008 · Here we show that antioxidant-1 (Atox1), previously appreciated as a copper chaperone, represents a novel copper-dependent transcription factor that mediates copper …

Human antioxidant protein 1 (Atox1) is a small cytosolic protein with an essential role in copper homeostasis. Atox1 functions as a copper carrier facilitating copper transfer to the secretory …

Here we show that copper stimulates cell proliferation in an Atox1-dependent manner. We also demonstrate that copper induces Atox1 nuclear translocation, binding to a novel cis element of …

Mar 14, 2024 · ATOX1 binds to Cu (I) in the cytoplasm and delivers it to copper-transporting ATPases, such as ATP7A and ATP7B, in the Golgi network 40 (Fig. 1).

Feb 8, 2025 · Atox1 has a role in copper transport to tumor cell nuclei. CTR1 silencing increased the protein levels of copper chaperone ATOX1 and copper chaperone for superoxide …

Dec 10, 2024 · Title: Memo1 binds reduced copper ions, interacts with copper chaperone Atox1, and protects against copper-mediated redox activity in vitro.

Sep 13, 2023 · The gene ATOX1 (NM_004045.3, NP_004036.1, antioxidant 1 copper chaperone, formerly HAH1) encodes a copper transport protein ATOX1, which is located on the fifth …

Antioxidant 1 (ATOX1), a chaperone of Cu previously named human ATX1 homologue (HAH1), has been found to play an indispensable role in maintaining cellular Cu homeostasis, …