The ATAC Acetyltransferase Complex Coordinates MAP Kinases to …
Sep 3, 2010 · We demonstrate that the ATAC (Ada two A containing) histone acetyltransferase (HAT) complex serves as a transcriptional cofactor for c-Jun at the Jun N-terminal kinase …
demonstrate that the ATAC (Ada two Acontaining) histone acetyltransferase (HAT) complex serves as a transcriptional cofactor for c-Jun at the Jun N-terminal kinase (JNK) target genes …
Cooperation between the Hippo and MAPK pathway activation …
Feb 18, 2025 · TEAD inhibitor resistant cells restore YAP and TEAD chromatin occupancy, acquire additional FOSL1 binding and exhibit increased MAPK (mitogen-activated protein …
Targeting the SAGA and ATAC transcriptional coactivator …
ATAC interacts with several MAPK pathway components during osmotic stress induction and may play a more prominent role than SAGA in this process . Targetable domains within the SAGA …
MAP kinase signalling cascades and transcriptional regulation
Jan 15, 2013 · The MAP kinase (MAPK) signalling pathways play fundamental roles in a wide range of cellular processes and are often deregulated in disease states. One major mode of …
The Double-Histone-Acetyltransferase Complex ATAC Is Essential …
Dec 22, 2008 · In addition, seven ATAC-specific components were discovered, including ADA2a, ZZZ3, mitogen-activated protein kinase (MAPK) upstream kinase-binding inhibitory protein …
Harnessing changes in open chromatin determined by ATAC-seq …
Our data from Drosophila S2 cells show that ATAC-seq and RNA-seq datasets are correlated, mainly driven by the ATAC-seq peaks/reads located in gene promoter regions. We also show …
Changes in the Transcriptome and Chromatin Landscape in BRAFi …
Jun 17, 2022 · In this study, we performed unbiased RNA-sequencing (RNA-seq) and assay for transposase-accessible chromatin with sequencing (ATAC-seq) to identify new targets and …
JUNB mediates oxaliplatin resistance via the MAPK signaling …
Nov 25, 2023 · Knockdown of JUNB inhibits the MAPK signaling pathway and restores sensitivity to oxaliplatin. Combined treatment with the ERK inhibitor piperlongumine or MEK inhibitor …
A Metazoan ATAC Acetyltransferase Subunit That Regulates …
Feb 18, 2012 · An ATAC subunit, dMoaE (CG10238), facilitates the recruitment of upstream kinases to JNK target genes and suppresses the levels of JNK activation in response to …