Nov 30, 2015 · A three minute introduction on the nucleic acid drugs made from APTAMER being developed by RIBOMIC Inc. http://www.ribomic.com/en/ ...more.

One type of unconventional nucleic acid is the aptamer. Aptamers are short, single stranded nucleic acids that fold into highly specific structures. They bind proteins or other biomolecular...

Nov 12, 2019 · Aptamers are these amazing molecules that are hoped will revolutionise medical processes. The Biotechn...more. This is an explainer video that shows the SELEX process. It …

A typical aptamer is a synthetically generated ligand exploiting the combinatorial diversity of DNA, RNA, XNA, or peptide to achieve strong, specific binding for a particular target molecule or …

Aug 8, 2019 · Here, we use a four-step approach to determine a true 3D structure of aptamers in solution using small-angle X-ray scattering (SAXS) and molecular structure restoration (MSR).

We investigated several methods for the estimation of aptamer-target molecule binding through conformational structure prediction, molecular docking, and molecular dynamic simulation.

Aptamers are short, single-stranded oligonucleotides that bind to specific target molecules. The shape-forming feature of single-stranded oligonucleotides provides high affinity and excellent …

Jan 1, 2025 · Aptamers are single-stranded DNA/RNA sequences that can bind with high affinity to a specific target molecule. There are several aptamers available for measuring dopamine. …

Jun 6, 2024 · We determined the tertiary complex structures of a newly discovered Clivia aptamer, which exhibits a small size and a large Stokes shift. Structural insights into the …

Jun 2, 2022 · Now, an artificial intelligence (AI)-powered tool called RaptGen is proposed for improving the successful identification of aptamer sequences. Aptamers are molecular …