Aug 21, 2024 · An APOE gene test is a type of genetic test that identifies which variant of the apolipoprotein E (APOE) genotype you have. Having certain APOE genotypes may mean you …

Apolipoprotein E (Apo-E) is a protein involved in the metabolism of fats in the body of mammals. A subtype is implicated in Alzheimer's disease and cardiovascular diseases. [5] . It is encoded in humans by the gene APOE. Apo-E belongs to a family …

Apolipoprotein (apo) E is a multifunctional protein with central roles in lipid metabolism, neurobiology, and neurodegenerative diseases. It has three major isoforms (apoE2, apoE3, and apoE4) with different effects on lipid and neuronal homeostasis.

Apolipoprotein E, or APOE, is a gene that comes in several forms, or alleles: APOE2, APOE3, and APOE4. Everyone carries 2 copies of this gene, one from each of their biological parents. Which APOE type you have, differentially impacts your risk for Alzheimer’s disease.

The APOE gene provides instructions for making a protein called apolipoprotein E. This protein combines with fats (lipids) in the body to form molecules called lipoproteins. Lipoproteins are …

Apolipoprotein (apo) E is a multifunctional protein with central roles in lipid metabolism, neurobiology, and neurodegenerative diseases. It has three major isoforms (apoE2, apoE3, and apoE4) with different effects on lipid and neuronal homeostasis.

Mar 28, 2025 · APOE (Apolipoprotein E) is a Protein Coding gene. Diseases associated with APOE include Lipoprotein Glomerulopathy and Hyperlipoproteinemia, Type Iii. Among its related pathways are Plasma lipoprotein assembly, remodeling, and clearance and Statin inhibition of cholesterol production.

Jul 31, 2019 · Polymorphism in the apolipoprotein E (APOE) gene is a major genetic risk determinant of late-onset Alzheimer disease (AD), with the APOE* ε 4 allele conferring an increased risk and the APOE*...

Apolipoprotein E (APOE) genotype is the major genetic risk factor for Alzheimer disease (AD); the ε4 allele increases risk and the ε2 allele is protective.

Jun 21, 2024 · For the past three decades, apolipoprotein E (APOE) has been known as the single greatest genetic modulator of sporadic Alzheimer disease (AD) risk, influencing both the average age of onset...