Acute promyelocytic anaemia is characterized by the presence of atypical promyelocytes and a t (15;17) translocation, resulting in a PML-RARA fusion. It is often associated with pancytopenia …

Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. [3] In APL, there is an abnormal accumulation of immature …

Jun 26, 2023 · Acute promyelocytic leukemia is a distinguished subset of acute myeloid leukemia which is characterized by fusion gene transcript PML-RAR-alpha and high cure rates with …

Mar 5, 2019 · Acute promyelocytic leukemia (APML) is a distinct subtype of acute myeloid leukemia. It is defined by a balanced translocation between chromosomes 15 and 17 resulting …

Apr 11, 2019 · Since the comprehensive recommendations for the management of acute promyelocytic leukemia (APL) reported in 2009, several studies have provided important …

Early diagnosis of acute promyelocytic leukemia (APL) is essential because of its associated life threatening coagulopathy and unique response to all trans-retinoic acid (ATRA) therapy. The …

May 21, 2024 · Acute promyelocytic leukaemia (APML) is a rare sub-type of acute myeloid leukaemia (AML) and is sometimes referred to as AML M31. APML accounts for only 10% of …

Dec 10, 2009 · Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML) with distinctive biologic and clinical features that is now highly curable. Most patients are …

Nov 14, 2024 · Acute myeloid leukaemia (AML) is a life-threatening haematological malignancy that predominantly occurs in older adults. Many subtypes exist; acute promyelocytic leukaemia …

Early diagnosis of acute promyelocytic leukaemia (APL) is essential because of its associated life-threatening coagulopathy and unique response to ATRA therapy.