An antigen-presenting cell (APC) or accessory cell is a cell that displays an antigen bound by major histocompatibility complex (MHC) proteins on its surface; this process is known as antigen presentation.

While all APCs play a similar role in adaptive immunity, there are some important differences to consider. Macrophages and dendritic cells are phagocytes that ingest and kill pathogens that penetrate the first-line barriers (i.e., skin and mucous membranes).

Apr 13, 2022 · Antigen processing and presentation are the cornerstones of adaptive immunity. B cells cannot generate high-affinity antibodies without T cell help. CD4 + T cells, which provide such help, use...

Apr 21, 2024 · While all APCs play a similar role in adaptive immunity, there are some important differences to consider. Macrophages and dendritic cells are phagocytes that ingest and kill pathogens that penetrate the first-line barriers (i.e., skin and mucous membranes).

Jul 18, 2013 · HLA class I antigens are expressed on all nucleated cells and platelets (except those of the central nervous system) while the HLA class II antigens are expressed on antigen presenting cells (APC) such as B lymphocytes, dendritic cells, macrophages, monocytes, Langerhans cells, endothelial cells, and thymic epithelial cells.

While all APCs play a similar role in adaptive immunity, there are some important differences to consider. Macrophages and dendritic cells are phagocytes that ingest and kill pathogens that penetrate the first-line barriers (i.e., skin and mucous membranes).

Antigen presentation is mediated by MHC class I molecules, and the class II molecules found on the surface of antigen-presenting cells (APCs) and certain other cells.

Antigen-presenting cells (APC) are cells that can process a protein antigen, break it into peptides, and present it in conjunction with class II MHC molecules on the cell surface where it may interact with appropriate T cell receptors.

An antigen-presenting cell (APC) or accessory cell is a cell that displays foreign antigen complexed with MHC on its surface. T-cells may recognize this complex using their T-cell receptor (TCR).

antigen have been bound by MHC molecules. Role of Antigen-Presenting Cells (APC) - Helper T cells: recognize antigen after processing and presentation by MHC-II on APC (dendritic cells, macrophages, B cells). - Cytotoxic T cells : recognize antigen when it is presented on MHC-I. - Since most nucleated cells in the body express class I MHC,