Feb 1, 2024 · The AOX pathway of mitochondrial electron transport is well known to coordinate with TCA cycle to sustain carbon and energy balance in a photosynthesizing cell particularly under biotic/abiotic stress conditions.

Jul 8, 2020 · Here we show impaired tumour growth in cancer cells that lack mitochondrial complex III. This phenotype was rescued by ectopic expression of Ciona intestinalis alternative oxidase (AOX) 12, which...

Alternative oxidase (AOX) is one of the terminal oxidases of the plant mitochondrial electron transport chain. AOX acts as a means to relax the highly coupled and tensed electron transport process in mitochondria thus providing and maintaining the ...

Jun 12, 2020 · The interaction of the alternative oxidase (AOX) pathway with nutrient metabolism is important for understanding how respiration modulates ATP synthesis and carbon economy in plants under nutrient deficiency.

To specifically restore the oxidative TCA cycle in mtDNA-depleted cells, we expressed two non-mammalian proteins, S. cerevisiae NDI1 (alternative NADH dehydrogenase) and C. intestinalis AOX (alternative oxidase), which can conduct electron flux but not proton pumping (Perales-Clemente et al., 2008). NDI1 can oxidize NADH and thus restore the ...

May 17, 2023 · The role of AOX in Ala-induced metabolism in plant mitochondria. In the wild-type mitochondria, upregulated AOX capacity induced by exogenous Ala treatment likely suppresses reactive oxygen species (ROS) production, ensuring …

Oct 27, 2020 · Results of recent studies indicate that the alternative oxidase (AOX) respiratory pathway may play an essential role in mediating cross-talk between ethylene response, carbon metabolism, ATP production, and ROS signaling during climacteric ripening.

Feb 1, 2024 · In higher plants, the mitochondrial alternative oxidase (AOX) pathway plays an essential role in maintaining the TCA cycle/cellular carbon and energy balance under various physiological and stress conditions.

In higher plants, the mitochondrial alternative oxidase (AOX) pathway plays an essential role in maintaining the TCA cycle/cellular carbon and energy balance under various physiological and stress conditions.

Dec 18, 2017 · The in vivo activation of the AOX pathway in leaves under HL has been linked to changes in key metabolites involved in non-cyclic flux modes of the TCA cycle, possibly supporting both photosynthetic (by dissipation of energy at photosystem II, PSII) and stress-related amino acid metabolism (Figure 1A).