Annexin is a common name for a group of cellular proteins. They are mostly found in eukaryotic organisms (animals, plants and fungi). In humans, the annexins are found inside the cell. However some annexins (Annexin A1, Annexin A2, and Annexin A5) can be secreted from the cytoplasm to outside cellular environments, such as blood.

Feb 21, 2024 · Annexins are cytosolic proteins with conserved three-dimensional structures that bind acidic phospholipids in cellular membranes at elevated Ca 2+ levels. Through this they act as Ca 2+...

May 4, 2004 · Annexins are traditionally thought of as calcium-dependent phospholipid-binding proteins, but recent work suggests a more complex set of functions. More than a thousand proteins of the annexin superfamily have been identified in major eukaryotic phyla, but annexins are absent from yeasts and prokaryotes.

Annexins are Ca2+ and phospholipid binding proteins forming an evolutionary conserved multigene family with members of the family being expressed throughout animal and plant kingdoms.

Annexins are a multigene family of Ca2+ -, phospholipid- and cytoskeleton-binding proteins with representatives in animals, plants and fungi [83–86]. They may exist in a soluble or membrane-bound state and, in plant cells, they may contribute up to 0.1% of the total protein.

Annexin A1 (ANXA1) has long been classed as an anti-inflammatory protein due to its control over leukocyte-mediated immune responses. However, it is now recognized that ANXA1 has widespread effects beyond the immune system with implications in ...

Jun 1, 2005 · Annexins are a multigene family of Ca 2+ -regulated proteins that are characterized by a unique Ca 2+ - and membrane-binding module — the annexin core domain. This core domain enables Ca 2+...

Feb 21, 2024 · Annexins are cytosolic proteins with conserved three-dimensional structures that bind acidic phospholipids in cellular membranes at elevated Ca²⁺ levels. Through this they act as Ca²⁺-regulated membrane binding modules that organize membrane lipids, facilitating cellular membra …

Nov 1, 2022 · Annexin (ANN) is a kind of protein family that widely exists in animals and plants and binds to membrane phospholipids in a calcium dependent manner. Since the first annexin was cloned from human cells (Creutz et al., 1978), more than 1000 annexin subfamily members have been found one after another. Among them, 13 annexin subfamily members were ...

May 4, 2004 · Annexins are traditionally thought of as calcium-dependent phospholipid-binding proteins, but recent work suggests a more complex set of functions. More than a thousand proteins of the annexin superfamily have been identified in major eukaryotic phyla, but annexins are absent from yeasts and prokary …