Dec 15, 2022 · Herein, we report a general photocatalytic platform for intermolecular allylic C–H amination of differently substituted alkenes with primary and secondary aliphatic amines to …

Allylic C–H amination is currently accomplished with (sulfon)amides or carbamates. Here we show the first allylic amination that can directly afford alkyl allylamines, enabled by the reactivity of …

Apr 14, 2022 · Metal-mediated allylic C–H amination provides an orthogonal methodology, where greater control of reactivity, selectivity, and functional group compatibility may be achieved.

Allylic Amination and N-Arylation-Based Domino Reactions Providing Rapid Three-Component Strategies to Fused Pyrroles with Different Substituted Patterns. The Journal of Organic …

A palladium-catalyzed allylic amination enables an asymmetric synthesis of α,α-disubstituted allylic N-arylamines from highly modular vinyl cyclic carbonates and unactivated aromatic …

Intramolecular Allylic Amination. Palladium-catalyzed allylic amination reaction through an intramolecular pathway, is an essential phase in heterocycle synthesis. Being able to perform …

Jul 22, 2022 · Here we report that the combination of a photocatalyst and cobaloxime enables site-selective amination of olefins with secondary alkyl amines to afford allylic amines, …

Mar 27, 2025 · In this study, we report the first ruthenium-catalyzed allylic substitution using ammonia. The catalytic system, consisting of [Cp*Ru(MeCN) 3 ]PF 6 and a phenoxythiazoline …

Mar 20, 2024 · Allylic amines are ubiquitous structural motifs found in drugs, natural products, and medicinally relevant molecules. We report here an “ionic-molecular” organocatalysis as a …

Sep 9, 2021 · Allylic amination enables late-stage functionalization of natural products where allylic C–H bonds are abundant, and introduction of nitrogen may alter biological profiles.