Effects of IFN-γ on the proliferation of 32D cells expressing Akt …
Interferon regulatory factor-1 (IRF-1) plays a critical role in the injury to stem and progenitor regions associated with aberrant interferon-gamma (IFN-γ) in aplastic anemia (AA). The …
Novel GM-CSF signals via IFN-γR/IRF-1 and AKT/mTOR license …
Jun 6, 2017 · This 2-step licensing of monocytes requires activation of the AKT/mTOR/mTORC1 signaling cascade by GM-CSF followed by signaling through the interferon-γ receptor (IFN …
Key role of interferon regulatory factor 1 (IRF-1) in regulating liver ...
Interferon regulatory factor 1 (IRF-1) is a member of the IRF family. It is the first transcription factor to be identified that could bind to the interferon-stimulated response element (ISRE) on …
B3GALT4 remodels the tumor microenvironment through GD2
Oct 25, 2022 · Mechanistically, B3GALT4 regulated the expression of CXCL9 and CXCL10 via the c-Met signaling in the lipid rafts and the downstream AKT/mTOR/IRF-1 pathway. The lipid …
Effects of IFN-γ on the proliferation of 32D cells expressing Akt …
The present study aimed to investigate the effects of IFN-γ on murine myeloid precursor cells (32D cells) with wild-type and inactive-type protein kinase B (Akt) after IRF-1 gene silencing. …
B3GALT4 remodels the tumor microenvironment through GD2 …
Oct 25, 2022 · Upregulation of B3GALT4 promotes the secretion of CXCL9 and CXCL10 to recruit CD8+ T lymphocytes via the GD2-mediated lipid rafts and the c-Met/AKT/mTOR/IRF-1 …
Effects of IFN-γ on the proliferation of 32D cells expressing Akt …
Jan 1, 2021 · The present study aimed to investigate the effects of IFN-γ on murine myeloid precursor cells (32D cells) with wild-type and inactive-type protein kinase B (Akt) after IRF-1 …
Interferon regulatory factor-1 (IRF-1) regulates VEGF-induced ...
Sep 1, 2008 · Interferon regulatory factor-1 (IRF-1) is a tumor suppressor and transcriptional modulator that can regulate gene expression involved in cell growth control, induction of …
Effects of Dp treatment on Akt/IRF1 signaling pathway in breast ...
Background: The long non-coding RNA (lncRNA) HOX transcript antisense RNA (HOTAIR) plays a crucial role in cancer progression, which is regulated by the interferon regulatory factor-1 …
XAF1 forms a positive feedback loop with IRF-1 to drive ... - Nature
Jul 24, 2018 · Here, we report that XAF1 forms a positive feedback loop with interferon regulatory factor-1 (IRF-1) and functions as a transcriptional coactivator of IRF-1 to suppress tumorigenesis.