Sep 13, 2018 · AMPK-ACC signaling in platelets is a key mechanism regulating primary hemostasis and arterial thrombosis. AMPK-ACC signaling controls collagen-induced TXA 2 …

Oct 10, 2003 · Phosphorylation of AMPK and acetyl-CoA carboxylase (ACC) are reduced with Akt overexpression and can be reversed by metformin. Neonatal rat cardiac myocytes infected …

Nov 3, 2013 · Acc activity in liver was measured by 14 CO 2 fixation into acid-stable products. Acc1 or Acc2 protein was immunoprecipitated from 2 mg of tissue homogenates using Acc1- …

Sep 13, 2018 · AMP-activated protein kinase (AMPK) α1 is activated in platelets on thrombin or collagen stimulation, and as a consequence, phosphorylates and inhibits acetyl-CoA …

Feb 1, 2022 · Based on the results, Ganoderma lucidum extract induces AMPK signaling phosphorylation to enhance expression level of GLUT1, GLUT4, protein kinase-B (Akt), IR …

Our study not only explains how Skp2 SCF E3 ligase is activated under EGF to trigger Akt ubi-quitination and activation, but also provides a possible resistant mechanism for anti-EGFR …

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We determined that the PI3K/Akt/IKK-alpha/NF-kappaB pathway is ubiquitously activated in ACC and plays an essential role in the evasion of apoptosis.

Nov 9, 2018 · PI3K/Akt signaling is activated in cancers and governs tumor initiation and progression, but how Akt is activated under diverse stresses is poorly understood. Here we …

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