The abilities of luteolin to reduce Vimentin and MMP9 expressions and to enhance E-cadherin expression were impaired in AIM2-knockdown A549 and H460 cells. Furthermore, AIM2 …

Jul 1, 2024 · It was found that luteolin significantly reduced the mRNA expression levels of AIM2, caspase-1, and IL-1β, thereby inhibiting the activation of the AIM2 inflammasome. Lutein …

Unlike in colorectal cancers, AIM2 has been found to function as an oncogene that promotes growth and proliferation in an inflammasome-dependent manner in lung carcinoma cell lines …

Sep 29, 2022 · In addition, AIM2 knockdown predominantly mitigated the EMT progression as judged by an increased level of E‐type marker CDH1 and the decreased levels of M‐type …

Jan 31, 2020 · Here, we demonstrate that the DNA sensor protein absent in melanoma 2 (AIM2) is highly expressed in non-small cell lung cancer (NSCLC) cells and that high AIM2 expression …

In the present study, we found that luteolin significantly reduced the expression of absent in melanoma 2 (AIM2) at both mRNA and protein levels leading to the suppression of AIM2 in …

Mar 4, 2019 · In the present study, we found that luteolin significantly reduced the expression of absent in melanoma 2 (AIM2) at both mRNA and protein levels leading to the suppression of …

The human absent in melanoma 2 (AIM2) is considered as a DNA recognizer. AIM2 has been described as a tumor suppressor gene in the early years. But recent studies suggested that it …

We found that the expression of AIM2 was highly expressed in H226, A549, A549/Taxol, and H460 cells compared with 16HBE cells (Fig. S2A). In addition, luteolin concentration …

Mar 4, 2019 · In this study, we indicated that luteolin suppressed the activation of AIM2 inflammasome by the downregulation of AIM2, thereby inducing G2/M phase arrest and …