Jan 25, 2023 · QM-FN-SO 3 (quinoline-malononitrile-thiophene- (dimethylamino)phenylsulfonate) is a near-infrared aggregation-induced-emission-active fluorescent probe capable of crossing the blood–brain...

Sep 1, 2022 · Herein, we designed a new AIE probe, LD-920, which was readily synthesized, and displayed good biocompatibility, high targeting ability for LDs, strong two-photon absorption, and far-red/near-infrared emission. The photostability of LD-920 is excellent both in one-photo and two-photon excitation.

Nov 1, 2024 · Zhong et al. developed a new type of “turn-on” AIE probe based on excited-state intramolecular proton transfer (ESIPT), with phenylboronic acid pinacol ester-appended quinolinium used as the H 2 O 2 recognition site due to the …

Jul 24, 2023 · Chen’s group explored the potential application of an AIE probe in neuroimaging. They reported an AIE-active probe, named PM-ML, that showed significant fluorescence enhancement in the aggregate state or upon interacting with phospholipid bilayers (Figure 7A).

Feb 1, 2025 · Developed and synthesized a multifunctional probe with POD activity and AIE properties. The α-glucosidase (α-GAA) in the identification of diabetes mellitus can be mutually verified with higher accuracy. Colorimetric-fluorescent dual-mode biosensors meet the urgency for precise diagnosis.

Feb 16, 2024 · Here, we developed an aggregation-induced emission (AIE) probe (MI-AIE-TsG, MAT) with dual activation for pan-cancer surgical navigation. MAT weakly activates fluorescence by targeting the SUR1 protein on the endoplasmic reticulum (ER) through the TsG group.

Jun 6, 2013 · The unique aggregation-induced emission (AIE) process offers a straightforward solution to the ACQ problem. Typical AIE fluorogens are characterized by their propeller-shaped rotorlike structures, which undergo low-frequency torsional motions as isolated molecules and emit very weakly in solutions.

Nov 9, 2021 · Chemical probes for the fluorescence imaging of myelin in 3D, especially in optically cleared tissue, are highly desirable but rarely reported. We herein developed a near-infrared aggregation-induced emission (AIE)-active probe, PM-ML, for high-performance myelin imaging.

Jan 1, 2022 · Fluorescent probes with aggregation-induced emission (AIE) properties have great potential in the biomedical field. In general, AIE fluorogens (AIEgens) are characterized by their excellent photostability and strong fluorescence signal when aggregated.

Apr 18, 2024 · Here we present a protocol for the design and synthesis of AGL nanoprobes with an aggregation-induced emission (AIE) effect to simultaneously red shift and amplify the afterglow signal...