An aglycone (aglycon [1] or genin) is the chemical compound remaining after the glycosyl group on a glycoside is replaced by a hydrogen atom. [2] For example, the aglycone of a cardiac glycoside would be a steroid molecule.

May 7, 2021 · Aglycone is the non-sugar compound remaining after replacement of the glycosyl group from a glycoside by a hydrogen atom.

Feb 28, 2022 · When the glycosyl group in a glycoside molecule is replaced by a hydrogen atom, the resulting compound, if not a carbohydrate, is called an aglycone. eg:

Jun 13, 2017 · In this review, we summarized the existing knowledge on the different biological benefits and pharmacokinetic behaviors between flavonoid aglycones and their glycosides.

…one or more other compounds—aglycones (nonsugars)—when hydrolyzed (chemically degraded by the introduction of water molecules between adjacent subunits), are extremely toxic to animals. Toxicity resides in the aglycone component or a part of it. Oxalates are salts of oxalic acid, which under natural conditions is not toxic but becomes…

The nonsugar moiety is called aglycone or genin, whereas sugar part is known as glycone [66]. The sugar and nonsugar moiety are linked by the glycosidic linkase [67]. The aglycone part is responsible for pharmacological action, whereas sugar part is responsible for solubility, cell permeability, and other pharmacokinetic properties [66,67 ...

Absorption and metabolism of glycosidic sweeteners of stevia mixture and their aglycone, steviol, in rats and humans.

Dec 24, 2024 · The term 'aglycone' refers to the non-glycosidic or non-carbohydrate component of a glycoconjugate. In biochemistry, glycoconjugates are molecules that consist of a carbohydrate (glycan) moiety linked to a non-carbohydrate (aglycone) moiety.

Owing to recent developments in molecular glycobiology a greater understanding has been gained of aglycon vs. glycoside activity and – based on these findings – it has become possible to develop new, more active or more effective glycodrugs.

Aglycone refers to the small molecule part of a glycoside that is not a sugar, and is often responsible for the biological activity of the compound. From: Understanding Medicinal Plants [2019], Paving the way towards effective plant-based inhibitors of hyaluronidase and tyrosinase: a critical review on a structure–activity relationship [2022 ...