AGAT catalyzes the formation of guanidinoacetate (GAA) that is methylated to creatine by guanidinoacetate methyltransferase (GAMT) which also uses SAM. The aim of the present …

Arginine:glycine amidinotransferase (AGAT) converts Arg to hArg and guanidinoacetate (GAA). While high concentrations of ADMA and low concentrations of hArg in the blood have been …

L - Arginine:glycine amidinotransferase (AGAT; EC 2.1.4.1) is the enzyme that catalyses the transfer of an amidino group from L - arginine to glycine. The products are L - ornithine and …

Jan 4, 2018 · Arginine:glycine amidinotransferase (AGAT) catalyzes the synthesis of L-homoarginine (hArg) from free Arg and l -lysine. Biological hArg is considered to occur …

Oct 19, 2012 · We studied biosynthesis of the cardiovascular risk factor homoarginine in humans. Arginine:glycine amidinotransferase (AGAT) is a key enzyme in creatine synthesis. Healthy …

Aug 18, 2021 · We therefore aimed to investigate the survival and cardiac outcome of AGAT knockout (Agat−/−) mice under hypoxia and a possible rescue of the phenotype. …

Mar 13, 2019 · Enzymes degrading ADMA [dimethylaminohydrolase 1 (DDAH1)] and synthesizing L-homoarginine [L-arginine:glycine amidinotransferase (AGAT)] are expressed in human …

Jun 27, 2015 · Back in the early 1990s, it was found that asymmetric dimethylarginine (ADMA), an arginine metabolite derived from l -arginine (Arg) residues in proteins by asymmetric …

Dec 1, 2018 · Arginine:glycine amidinotransferase (AGAT) catalyzes the synthesis of L-homoarginine (hArg) from free Arg and L-lysine. Biological hArg is considered to occur …

Jun 2, 2015 · AGAT catalyzes the formation of guanidinoacetate (GAA) that is methylated to creatine by guanidinoacetate methyltransferase (GAMT) which also uses SAM. The aim of the …