In organic chemistry, an acyl chloride (or acid chloride) is an organic compound with the functional group −C (=O)Cl. Their formula is usually written R−COCl, where R is a side chain. They are reactive derivatives of carboxylic acids (R−C (=O)OH). A specific example of an acyl chloride is acetyl chloride, CH3COCl.

Acyl chlorides (also known as acid chlorides) are one of a number of types of compounds known as "acid derivatives". This is ethanoic acid: If you remove the -OH group and replace it by a -Cl, you have produced an acyl chloride.

This page explains what acyl chlorides are and looks at their simple physical properties such as boiling points. It introduces their chemical reactivity in a general way, but details of specific reactions are given on separate pages - see the acyl chlorides menu (link …

May 25, 2023 · Acyl chloride is an important derivative of carboxylic acid. It has an sp 2 hybridized carbonyl group with an O atom connected to a C atom through a double bond in a planar form with bond angles of about 120 o. It is an organic molecule composed of a …

Acid chlorides, or acyl chlorides, are derivatives of carboxylic acids that have a chlorine atom directly attached to the carbonyl group. Due to the polarization of the carbonyl and inductive effect of the chlorine atom, acid chlorides are quite electrophilic …

In chemistry, an acyl group is a moiety derived by the removal of one or more hydroxyl groups from an oxoacid, [1] including inorganic acids. It contains a double-bonded oxygen atom and an organyl group (R−C=O) or hydrogen in the case of formyl group (H−C=O).

Jan 23, 2023 · This page looks at ways of swapping the -OH group in the -COOH group of a carboxylic acid for a chlorine atom. This produces useful compounds called acyl chlorides (acid chlorides). It covers the use of phosphorus(V) chloride and phosphorus(III) chloride as well as sulfur dichloride oxide (thionyl chloride).

Acyl chlorides, being the most reactive among carboxylic acids derivatives, undergo a wide variety of nucleophilic acyl substitution reactions. A quick reminder, in a nucleophilic acyl substitution, the leaving group is replaced by a nucleophile by the addition-elimination mechanism:

Oct 26, 2024 · Learn about acylation mechanism for your A-level chemistry exam. Find information on acid chlorides, nucleophilic attack and reaction conditions.

An acyl chloride (or acid chloride) is an organic compound with the functional group -COCl in organic chemistry. Acid chlorides are used to make acid anhydrides, amides, and esters by reacting them with a salt of a carboxylic acid, an amine, or alcohol, respectively.