Oct 22, 2021 · Here, we demonstrate that during Th cell differentiation the methyltransferase activity of the PcG protein Ezh2 regulates post-transcriptionally inducible assembly of …

Sep 9, 2021 · Here, we demonstrate that during Th cell differentiation the methyltransferase activity of the PcG protein Ezh2 regulates post-transcriptionally inducible assembly of …

Sep 15, 2020 · Interference of force-induced EZH2 reduction could drive actin filaments dependent spatial overlap between EZH2 and super-enhancers and functionally compromise …

May 6, 2005 · The role of Ezh2 in actin polymerization bears important functional implications. Ezh2 deficiency renders peripheral T cells poorly responsive to proliferative signals induced by …

Feb 12, 2024 · EZH2 acts as the catalytic subunit of PRC2 to trimethylate histone H3 at lysine 27 (H3K27me3) to promote epigenetic gene silencing during development.

Jun 15, 2017 · Disruption of TUG1 abolished the interaction of EZH2 with α-actin, and accelerated depolymerization of F-actin in VSMCs. Based on EZH2 methyltransferase activity and the …

Jul 5, 2021 · Loss of epithelial TAK1, EZH2 or blocking nuclear actin influx attenuates the fibrotic cascade and restores respiratory homeostasis. Accordingly, EZH2 inhibition significantly …

Here, we demonstrate that during Th cell dif-ferentiation the methyltransferase activity of the PcG protein Ezh2 regulates post-transcriptionally inducible assembly of intranuclear actin filaments.

Sep 1, 2021 · Here, we demonstrate that during Th cell differentiation the methyltransferase activity of the PcG protein Ezh2 regulates post-transcriptionally inducible assembly of …

Feb 15, 2023 · Pharmacological blockade of EZH2 inhibits CRACD-negative SCLC tumorigenesis by restoring MHC-I expression and immune surveillance. Unsupervised single-cell …