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    Nature
    https://www.nature.com › articles

    Transcriptional regulation and small compound targeting of ACE2 …

    • Angiotensin-converting enzyme 2 (ACE2) is the receptor of COVID-19 pathogen SARS-CoV-2, but the transcription factors (TFs) that regulate the expression of the gene encoding ACE2 (ACE2) h… See more

    Introduction

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen of coronavirus … See more

    Nature
    Materials and methods

    Patient samples
    This study was approved by the Research Ethics Committee of the Chinese Academy of Medical Sciences Cancer Institute and Hospital. Al… See more

    Nature
    Results

    Transcription factors that can regulate ACE2 expression
    The Cistrome Data Browser (DB) that is a resource derived from chromatin immunopre… See more

    Nature
    Discussion

    The application of TCM has an important role in China’s containment of COVID-19 [26, 32]. Current findings have shown that TCM can reduce the incidence of viral infections, … See more

    Nature
    Acknowledgements

    This work was jointly supported by the Key Project of the National Natural Science Foundation of China (81830093), the National Key Research and Development Program o… See more

    Nature
    What is ATAC-seq data analysis?
    Assay of Transposase Accessible Chromatin sequencing (ATAC-seq) is widely used in studying chromatin biology, but a comprehensive review of the analysis tools has not been completed yet. Here, we discuss the major steps in ATAC-seq data analysis, ...
    pmc.ncbi.nlm.nih.gov
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