Aggrecan - Wikipedia
Aggrecan (ACAN), also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded by the ACAN gene. [5] This gene is a member of the lectican (chondroitin sulfate proteoglycan) family.
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ACAN mutations as a cause of familial short stature - PMC
At least 25 pathological ACAN mutations have been identified in patients with highly variable phenotypes of syndromic or non-syndromic short stature. This review provides an overview of the current understanding of ACAN and the clinical and genetic findings concerning aggrecan-associated diseases.
ACAN Gene - GeneCards | PGCA Protein | PGCA Antibody
Mar 30, 2025 · ACAN (Aggrecan) is a Protein Coding gene. Diseases associated with ACAN include Spondyloepimetaphyseal Dysplasia, Aggrecan Type and Spondyloepiphyseal Dysplasia, Kimberley Type. Among its related pathways are Integrin …
ACAN gene - MedlinePlus
Aggrecan is a type of protein known as a proteoglycan, which means it has several sugar molecules attached to it. It is the most abundant proteoglycan in cartilage, a tough, flexible tissue that makes up much of the skeleton during early development.
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ACAN Stock Price | Americann Inc. Stock Quote (U.S.: OTC) - MarketWatch
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Genotype and phenotype in patients with ACAN gene variants
No clear genotype-phenotype relationship of patients with ACAN variants was found. Gene sequencing is necessary to diagnose ACAN variants that cause short stature. In general, appropriate rhGH and/or GnRHa therapy can improve the adult height of affected pediatric patients caused by ACAN variants.
High frequency of pathogenic ACAN variants including an …
Our results expanded the number of pathogenic ACAN variants, including the first intragenic deletion, and suggested CNV evaluation in patients with typical clinical features of aggrecanopathy as reasonable. Intra-familial phenotypic variability in …
Advisory Committee on Antarctic Names - Wikipedia
The Advisory Committee on Antarctic Names (ACAN or US-ACAN) is an advisory committee of the United States Board on Geographic Names responsible for recommending commemorative names for features in Antarctica.