STUB1 is acetylated by KAT5 and alleviates myocardial ischemia ...
Apr 1, 2024 · Our findings suggest that KAT5 overexpression inhibits NLRP3-mediated cardiomyocyte pyroptosis to relieve MIRI through modulation of STUB1/LATS2/YAP/β-catenin …
Senescence in human AC16 cardiac cells is associated with …
Senescence associated β-galactosidase (Sigma) staining was performed following the manufacturer's protocol. Briefly, AC16 cells were treated with 0.1 µM doxorubicin or vehicle for …
Systematic transcriptomic and phenotypic characterization of …
Apr 1, 2022 · Organized sarcomeric structure is detectable in HL-1 cells but not in H9C2 or AC16. Differentiation of AC16 or H9C2 induces minor changes towards cardiac phenotype. …
IFI-16 inhibition attenuates myocardial remodeling following …
Aug 16, 2024 · Co-immunoprecipitation (coIP) and double-fluorescence staining confirmed IFI-16’s ability to interact directly with galectin-3. These findings underscore IFI-16’s critical role as …
TMEM65 regulates and is required for NCLX-dependent ... - Nature
5 days ago · b, Immunofluorescence staining of AC16 cardiomyocytes transiently transfected with a plasmid encoding TMEM65-Myc-FLAG or empty vector control, corresponding to experiment …
miR-16-5p Regulates PTPN4 and Affects Cardiomyocyte Apoptosis …
Silencing PTPN4 reverses the inhibitory effect of knockdown of miR-16-5p on H/R-induced AC16 cell damage: (a) PYPN4 protein in AC16 cells; (b) LDH levels in AC16 cells; (c) CK-MB levels …
The activation of LBH-CRYAB signaling promotes cardiac …
May 17, 2024 · (E) FerroOrange staining in live CYRAB-overexpressed AC16 cells under erastin treatment. The limb-bud and heart-αB-crystallin axis affects p53 signaling via both protein …
Deduction of novel genes potentially involved in hypoxic AC16 …
The present study aimed to identify differentially expressed genes in hypoxic human AC16 cardiomyocytes using next-generation sequencing and bioinformatics. A total of 24 genes (15 …
Role of pyroptosis in normal cardiac response to calorie restriction ...
Jan 1, 2018 · TUNEL staining was performed to evaluate DNA damage in AC16 cells. HE and Masson staining were performed to detect the morphology and degree of fibrosis in …
AC16 cell comparing the safety of different thrombolytic drugs.
Cytoskeleton stained by β-TUBULIN and nuclear stained DAPI of AC 16 cells after the treatment of the three drugs; green: cytoskeleton, blue: nuclear (D). The data are presented as the mean...