CREB1 Encodes a Nuclear Activator, a Repressor, and a …
Oct 16, 1998 · The CREB1α mRNA encodes the CREB1a transcriptional activator, and the bicistronic CREB1β mRNA encodes two additional CREB1 isoforms: the first ORF encodes …
CREB1 and ATF1 Negatively Regulate Glutathione Biosynthesis Sensitizing ...
Jun 10, 2021 · Here we found that CREB1 and ATF1 unexpectedly regulate glutathione (GSH) biosynthesis by suppressing the expression of glutamate-cysteine ligase modifier subunit …
The α and Δ Isoforms of CREB1 Are Required to Maintain Normal …
We show that a CREB1 mutation that leads to loss of these two isoforms, causes increased pulmonary vascular resistance in both normoxia and hypoxia, demonstrating that normal …
Increased mAb production in amplified CHO cell lines is associated …
Results presented here suggest increased association of CREB1 with the nucleus in the high producer cell line A1 compared with the parental A0 clone. CREB1 is a well-studied …
Integrated bioinformatics approach to unwind key genes and …
Oct 1, 2023 · The present study proposed five novel therapeutic targets, i.e., ATM, GAPDH, CREB1, VEGFA, and CDH1 genes that might provide new insights into molecular …
TGF-β1-ROS-ATM-CREB signaling axis in macrophage mediated ... - PubMed
This, in turn, increased expression of cAMP response element binding protein (CREB) and vimentin resulting in migration of cells. These effects were inhibited by neutralization of TNF-α, …
Multi-faceted regulation of CREB family transcription factors
Aug 6, 2024 · cAMP response element-binding protein (CREB) is a ubiquitously expressed nuclear transcription factor, which can be constitutively activated regardless of external stimuli …
ATM/CK cluster positively and negatively regulates CREB
cAMP response element binding protein (CREB) is a key regulator of glucose metabolism and synaptic plasticity that is canonically regulated through recruitment of transcriptional...
CREB1 cAMP responsive element binding protein 1 [ (human)]
Dual-Specificity Phosphatase 4 Promotes Malignant Features in Colorectal Cancer Through Cyclic-AMP Response Element Binding Protein/Protein Kinase CAMP-Activated Catalytic …
CCDC6: the identity of a protein known to be partner in fusion
Oct 16, 2017 · CCDC6 binds to the transcription factor CREB1, which is known to regulate transcription of proteins involved in cell proliferation (Fig. 2). 67 CCDC6 represses CREB1 …