E2F2 - Wikipedia
The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F …
Regulation of a Novel Androgen Receptor Target Gene, the Cyclin …
The molecular mechanisms of AR signaling in the stroma are poorly defined. In this study, we explored the mechanism, involving E2Fs and AR, through which androgen suppresses the …
A critical role of E2F transcription factor 2 in proinflammatory ...
Feb 8, 2018 · To investigate the role and mechnism of E2F2 in RA, expression of E2F2 in synovial tissue was detected. Proliferation, invasion, and secretion of inflammatory cytokines …
E2f1, E2f2, and E2f3 Control E2F Target Expression and Cellular ...
Using a conditional gene-targeting approach, we show that the targeted disruption of the entire E2F activator subclass composed of E2f1, E2f2, and E2f3 in mouse embryonic fibroblasts …
The E2F transcription factor 2: What do we know? - PubMed
May 11, 2021 · This review focuses on genetic studies that have helped elucidate the biological functions of E2F2 and that have enhanced our understanding of how E2F2 is integrated into …
E2F - Wikipedia
E2F is a group of genes that encodes a family of transcription factors (TF) in higher eukaryotes. Three of them are activators: E2F1, 2 and E2F3a. Six others act as repressors: E2F3b, E2F4 …
(PDF) The E2F transcription factor 2: What do we know?
Apr 29, 2021 · This review focuses on genetic studies that have helped elucidate the biological functions of E2F2 and that have enhanced our understanding of how E2F2 is integrated into …
Atypical E2Fs: new players in the E2F transcription factor family
Feb 9, 2009 · Unlike other family members, atypical E2Fs have a duplicated DNA-binding domain and control gene expression without heterodimerization with dimerization partner proteins.
The E2F transcription factor 2: What do we know? - J-STAGE
Apr 30, 2021 · This review focuses on genetic studies that have helped elucidate the biological functions of E2F2 and that have enhanced our understanding of how E2F2 is integrated into …
The genetics of the E2F family of transcription factors: shared ...
Jun 21, 2002 · What started as a simple model of positive regulation of genes required for DNA synthesis by E2F has markedly expanded. E2F now appears to play contrasting roles in …