Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. [3] In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes.

Acute promyelocytic leukemia (APL) is a rare blood cancer that once was a fatal illness. Now, healthcare providers consider APL a curable disease, thanks to an innovative combination of chemotherapy and non-chemotherapy drugs.

Prompt diagnosis and treatment of acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia (AML), is very important because people with APL can quickly develop life-threatening blood-clotting or bleeding problems if not treated.

May 7, 2015 · Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML) in which cells in the bone marrow that produce blood cells (red cells, white cells and platelets) do not develop and function normally. APL begins with one or more acquired changes (mutations) to the DNA of a single blood-forming cell.

Acute promyelocytic leukemia (APL) is an aggressive type of acute myeloid leukemia (AML). It happens when there are too many of the blood-forming cells called promyelocytes in the blood and bone marrow.

Jun 26, 2023 · Acute promyelocytic leukemia is a distinguished subset of acute myeloid leukemia which is characterized by fusion gene transcript PML-RAR-alpha and high cure rates with treatment.

May 24, 2023 · Acute promyelocytic leukemia (APL) is a type of acute myeloid leukemia (AML). With proper treatment, the survival rates are high. APL is a relatively rare cancer, accounting for about 7–8% of...

Oct 4, 2021 · APL accounts for 10% of acute myeloid leukemia. APL tends to affect younger patients than other types of acute myeloid leukemia (the median age of APL onset is 40 years old).

May 21, 2024 · Acute promyelocytic leukaemia (APML) is a rare sub-type of acute myeloid leukaemia (AML) and is sometimes referred to as AML M31. APML accounts for only 10% of all AML diagnoses. In APML, immature abnormal neutrophils (a type of white blood cell) known as promyelocytes accumulate in the bone marrow. These immature cells are unable to mature and ...

Acute promyelocytic leukemia (APL) is a rare subtype of acute myeloid leukemia that leads rapidly to death if untreated. The characteristic morphology of promyelocytic blasts in combination with the genetic detection of the chromosome translocation t(15;17)(q22;q21) or the fusion gene PML::RARA allow the clear diagnosis of APL.