Acute monocytic leukemia (AMoL, or AML-M5) [2] is a type of acute myeloid leukemia. In AML-M5 >80% of the leukemic cells are of monocytic lineage. [ 3 ] This cancer is characterized by a dominance of monocytes in the bone marrow.

Acute Myeloid Leukemia (AML) Subtypes and Prognostic Factors For most types of cancer, determining the stage (extent) of the cancer is very important. The stage is based on the size of the main tumor and how far the cancer has spread.

Acute monocytic leukemia (AMoL, or AML-M5) is considered a type of acute myeloid leukemia (AML). In order to fulfill World Health Organization (WHO) criteria for AML-M5, a patient must have greater than 20% blasts in the bone marrow, and of these, greater than 80% must be of the monocytic lineage.

Aug 24, 2021 · AML is a type of leukemia that develops quickly (acute) and affects myeloid cells (myeloid). AML-M5 is a subtype of AML that mainly affects the growth of monocytes. Monocytes have the potential...

Mar 17, 2025 · Acute monocytic leukemia (AMoL) is a type of acute myeloid leukemia (AML). It’s also known as AML-M5. It happens when immature cells that are on track to develop into white blood cells (monocytes) turn cancerous. The most common treatments are chemotherapy and stem cell transplants.

Acute myelomonocytic leukemia (AMML) is a form of acute myeloid leukemia that involves a proliferation of CFU-GM myeloblasts and monoblasts. AMML occurs with a rapid increase amount in white blood cell count and is defined by more than 20% of myeloblast in the bone marrow.

We propose that AML‐M5 children with any of MLL‐rearrangement, FLT3‐ITD, hyperleukocytosis, BM blast ≥ 70%, or age ≤ 3 years old are classified into the high‐risk group, and HSCT is beneficial especially in patients with FLT3‐ITD mutation, hyperleukocytosis, and age ≤ 3 years old.

Feb 1, 2013 · Acute monoblastic and acute monocytic leukemia (AML M5) 10% of AML cases High incidence of bleeding disorders (including DIC), organomegaly, lymphadenopathy, gingival hyperplasia, CNS and other tissue involvement (monocytes infiltrate)

Acute monocytic leukemia is a distinct subtype of acute myeloid leukemia (AML) with characteristic biologic and clinical features. This study was designed to compare the outcome of patients with M5 to that of other subtypes of AML, and to identify differences in M5a and M5b.

Acute monoblastic leukemia (AML-M5), is one of the most common subtypes of acute myeloid leukemia (AML) that is either comprised of more than 80% of monoblasts (AML-M5a) or 30-80% monoblasts with (pro)monocytic differentiation (AML-M5b). AML-M5 presents with asthenia, pallor, fever, and dizziness.