Nov 15, 2011 · Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is an important contributor to population morbidity and mortality. An arrhythmia that is particularly common in the elderly, AF is growing in prevalence with the aging of the population.

Feb 1, 2010 · In this issue of the Circulation: Arrhythmia and Electrophysiology, Kurotobi et al 1 determined the number of arrhythmogenic foci in atria provocable with isoproterenol infusion in patients with paroxysmal, persistent, and permanent atrial fibrillation (AF). The results show that persistent AF has more foci than paroxysmal AF.

In this article, we attempt a broad review of the known pathophysiological mechanisms of AF, and we present the recent efforts of advanced technology initially to reveal the electrical impulse during AF and then to intervene effectively with ablation. 1. Introduction.

It is now known that foci of rapid ectopic activity, often located in muscular sleeves that extend from the left atrium into the proximal parts of pulmonary veins, play a pivotal role in the initiation of AF in humans. 3 Less frequently, focal initiation of AF may be result from ectopic activity that arises from muscular sleeves in the proximal ...

Feb 1, 2021 · In 1998, Haïssaguerre, et al., demonstrated that 94% of atrial ectopic foci initiating AFib were localized to the pulmonary veins (PVs), and focal ablation of these foci eliminated AFib in a majority of patients. 1 In 2000, Pappone, et al., introduced the anatomical approach for PV isolation using circumferential lesion sets around PV ostia. 2

Apr 26, 2023 · Atrial fibrillation is the most common type of cardiac arrhythmia. It is the leading cardiac cause of stroke. Risk factors for atrial fibrillation include advanced age, high blood pressure, underlying heart and lung disease, congenital heart …

Dec 8, 2009 · In this study, we clarified the significance of multiple foci in the development of atrial fibrillation (AF) persistency. Two hundred fourteen consecutive patients with AF undergoing catheter ablation were enrolled in this study. We detected 500 arrhythmogenic foci.

Oct 8, 2024 · Atrial fibrillation (AF) is the most common sustained arrhythmia. It is characterised by disorganised atrial electrical activity and contraction. The incidence and prevalence of AF is increasing. Lifetime risk over the age of 40 years is ~25%.

In this issue of the journal, Kurotobi et al 1 determined the number of arrhythmogenic foci in atrial provokable with isoproterenol infusion in patients with paroxysmal, persistent and permanent atrial fibrillation (AF). The results show that persistent AF has more foci than paroxysmal AF.

Sep 15, 2016 · Atrial fibrillation is a supraventricular arrhythmia that adversely affects cardiac function and increases the risk of stroke. It is the most common arrhythmia and a major source of morbidity...