ATP-binding cassette sub-family G member 5 is a protein that in humans is encoded by the ABCG5 gene. [5][6][7] The protein encoded by this gene is a member of the superfamily of …

Mar 28, 2025 · Complete information for ABCG5 gene (Protein Coding), ATP Binding Cassette Subfamily G Member 5, including: function, proteins, disorders, pathways, orthologs, and …

Jan 20, 2014 · ATP-binding cassette (ABC) transporters G5 (ABCG5) and G8 (ABCG8) form an obligate heterodimer that limits intestinal absorption and facilitates biliary secretion of …

The ABCG5 gene provides instructions for making sterolin-1, which makes up half of a protein called sterolin. Learn about this gene and related health conditions.

Sitosterolemia is a lipid disorder characterized by the accumulation of dietary xenosterols in plasma and tissues caused by mutations in either ABCG5 or ABCG8. ABCG5 ABCG8 …

Feb 8, 2025 · ATP-binding cassette (ABC) transporters G5 (ABCG5) and G8 (ABCG8) form an obligate heterodimer that limits intestinal absorption and facilitates biliary secretion of …

In this review, we summarize recent pathophysiological and structural findings of ABCG5/G8, interpret the structure-function relationship in disease-causing variants and describe the …

In this review, we summarize the genetics and mechanisms of sitosterolemia and sterol trafficking, and provide an update on the understanding of the prevalence of ABCG5 and ABCG8 variants …

Aug 30, 2020 · Here, we explored the metabolic and clinical consequences of ABCG5 or ABCG8 deficiency. We recruited probands and relatives in sitosterolemia families and assessed …

The gene (called ABCG5) consists of 13 exons, and encodes a 651-residue, 70 kD protein with 6 putative membrane-spanning domains that contains the characteristic ABC signature motifs at …