ABCE1 is an essential and highly conserved protein that is required for both eukaryotic translation initiation as well as ribosome biogenesis. The most studied homologues are Rli1p in yeast and …

Mar 28, 2025 · ABCE1 (ATP Binding Cassette Subfamily E Member 1) is a Protein Coding gene. Diseases associated with ABCE1 include Prostate Cancer and Congenital Myopathy 22B. …

Results suggest that ABCE1 plays an important role in the pathogenesis of human small cell lung cancer cell. NTP hydrolysis by ABCE1 is stimulated by posttermination complexes and is …

Feb 4, 2020 · Here, we newly identified that ATP-binding cassette sub-family E member 1 (ABCE1), which is also known as RNase L inhibitor (RLI), is involved in the regulation of …

Based on an extended analysis of our recently published late-stage 48S initiation complex from rabbit, here we provide new mechanistic insights into this putative role of ABCE1 in initiation.

Here we report that ABCE1, a conserved and essential member of the ATP-binding cassette (ABC) family of proteins, promotes eukaryotic ribosomal recycling over a wide range of Mg 2+ …

Here, we show that the ATP-binding cassette E1 (ABCE1) transporter, identified as an inhibitor of RNase L, regulates RNase L activity and RNase L-induced autophagy during viral infections. …

Jul 29, 2021 · ATP-binding cassette subfamily E member 1 (ABCE1) belongs to the ABC protein family of transporters; however, it does not behave as a drug transporter. Instead, ABCE1 …

By forming a heterodimer with RNase L, ABCE1 protein inhibits the IFN-depended 2-5A/RNase L system and regulates a broad range of biological functions including viral infection, tumor cell …

Three rare and potentially damaging de novo missense variants in the ABCE1 gene have been identified in ASD probands from the Simons Simplex Collection and the SPARK cohort …