Ever wondered what makes kratom such a powerful pain-reliever? This article explains 7-hydroxymitragynine, the chemical behind kratom’s analgesic properties.

7-Hydroxymitragynine (7-OH), a metabolite of the psychoactive botanical kratom, exhibits significantly higher binding affinity to mu-opioid receptors (MOR) than morphine, with estimates ranging from 14 to 22 times greater potency.

Sep 4, 2024 · 7-OH is one of the primary active alkaloids in kratom, albeit present in smaller quantities compared to mitragynine. Despite its lower concentration, 7-OH is significantly more potent, contributing to kratom's analgesic and mood-enhancing effects.

7-Hydroxymitragynine, also called 7-OH mitragynine or 7-OH, is an active metabolite of mitragynine, the kratom plant’s principal psychoactive alkaloid. This substance is critical in enhancing mitragynine’s pain-relieving effects by strongly activating mu-opioid receptors, similar to …

Oct 28, 2024 · When exploring the complex world of kratom, you might come across the name 7-Hydroxymitragynine (or 7-OH). It’s one of the most important alkaloids found in kratom, and its potency can be surprising to many. But what exactly makes 7-OH so powerful?

Mar 14, 2025 · 7-Hydroxymitragynine, or 7-OHMZ, is an alkaloid primarily found in kratom (Mitragyna). This natural compound is made by the kratom plant in small quantities, yet it is much more potent than mitragynine, kratom’s main alkaloid.

Jan 31, 2025 · 7OH (7-hydroxy mitragynine) is kratom's most potent alkaloid and a popular alternative for those seeking natural relief. Studies have shown that it's roughly 40x stronger than kratom's primary alkaloid, mitragynine. Find it online with Modus 7-OH Capsules, Tablets, Shots, and Gummies—ranging from 10mg to 30mg 7-OH.

Mar 30, 2025 · 7OH is the powerhouse alkaloid in kratom, approximately 13 times more potent than mitragynine, making it the primary component responsible for kratom’s discomfort-relieving effects. Rather than focusing on strain names, experienced users should seek products with verified 7OH content, which delivers more consistent and powerful results with ...

Dec 16, 2024 · Among its most potent components is 7-hydroxymitragynine, also known as 7-Hydroxy or 7OH, a compound that plays a pivotal role in kratom’s effects. But what exactly is 7OH? Why is it such a big player in the effects of the well-known Kratom?

Jan 17, 2025 · Exploring alternative and holistic healing methods has led many to discover kratom, specifically 7-hydroxymitragynine (7-OH), a powerful compound found in the kratom leaf. Here, explore the top benefits of 7-OH kratom for pain relief.