4-Methoxyphencyclidine (methoxydine, 4-MeO-PCP) is a dissociative anesthetic drug that has been sold online as a research chemical. The synthesis of 4-MeO-PCP was first reported in 1965 by the Parke-Davis medicinal chemist Victor Maddox. [1]

We explored their mechanism of action by pretreating dopamine receptor (DR) D1 antagonist SCH23390 and DRD2 antagonist haloperidol during CPP test and investigated the effects of 4-MeO-PCP and 3-MeO-PCMo on dopamine-related proteins in the ventral tegmental area and nucleus accumbens.

Information about 4-MeO-PCP including basics, effects, dosage, history, legal status, photos, research, media coverage, and links to other resources.

UN Member States reported 4-MeO-PCP as the most common PCP-type substance. Description. Phencyclidine-type substances act predominantly either as central nervous system stimulants, or dissociatives.

4-MeO-PCP. Although 4-MeO-PCP was synthesized in the 1960s, it appeared on the narcotics market in 2008 as one of the first “dissociative research chemicals” . Many isomers or other structurally similar molecules have since appeared, which …

This is the ultimate guide to 4-MeO PCP. You will learn about its effects, benefits, dangers, and how to take 4-MeO PCP safely!

Jun 2, 2011 · 4-MeO-PCP is dissociative and sedative research chemical. It possesses both euphoric and analgesic effects at low doses, and can cause hallucinations at high doses. It is less potent than 3-MeO-PCP, and PCP. The onset is approximately 2.5 hours for effects to peak. The effects can last 8-12 hours.

An arylcyclohexamine dissociative anaesthetic related to PCP. First discovered in the 1960s by Parke-Davis, it was introduced to the RC market in 2008. Reported to be less potent than PCP.

4-Methoxyphencyclidine (abbreviated 4-MeO-PCP) is a synthetic dissociative of the arylcyclohexylamine class which produces hallucinogenic and anesthetic effects. The synthesis of 4-MeO-PCP was first reported in 1965 by the Parke-Davis medicinal chemist Victor Maddox.

4-MeO-PCP is a dissociative PCP analog. It is most often found in powder form that is taken nasally, orally, or via rectal administration. Dosage data is quite tentative; Some possibly because of variations in potency in available supplies.